Zocor primarily lowers cholesterol by inhibiting the HMG-CoA reductase enzyme. The liver uses this enzyme to synthesise cholesterol. By blocking HMG-CoA reductase, which lowers LDL cholesterol, Zocor reduces the production of cholesterol. Moreover, it has been demonstrated that a 10 mg simvastatin tablet marginally increases HDL cholesterol levels, improving the lipid profile overall.
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