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HSCT (hematopoietic stem cell transplantation) and BMT (bone marrow transplant) are often used interchangeably, but there are key distinctions between these procedures. The essence of both procedures is healthy stem cell transplantation for damaged or diseased bone marrow; however, transplantation may be carried out from several different sources. In this blog, we learn more about the similarities and differences between HSCT and BMT.
Stem cells are atypical cells that have a unique capability for self-renewal as well as divergent potential. That is, they can transform themselves into different types of blood cells such as red blood cells, white blood cells, and platelets. These stem cells are indispensable for restoring blood-forming capacity in the body when used in transplantation therapy.
HSCT is a more global term that encompasses the entire spectrum of stem cell transplants used for the treatment of different blood disorders, as well as cancers. The word 'hematopoietic' comes from the stem word, which signifies the process of blood cell formation. In HSCT, stem cells can be derived from different sources, including:
Bone marrow transplant (BMT) is a specialized treatment for patients with specific malignancies or other diseases. A bone marrow transplant involves removing the stem cells that generally reside inside bone marrow, processing those cells, and substituting these for the donor (patient) or another recipient. While a specific approach towards stem-cell transplantation, the BMT is an ancestor of HSCT, or a broader definition altogether, due to technological advancements offering other options in harvesting stem cells as well.
The key differences between Hematopoietic stem cell transplantation and Bone marrow transplant are:
Both HSCT and BMT follow a similar general procedure:
The healthcare team does an assessment and decides what would be best in terms of treatment, and then factors such as diagnosis, the health status of the patient, and donor availability determine whether hematopoietic stem cell transplant (HSCT) or bone marrow transplant (BMT) will be advised.
Transplantation of hematopoietic stem cells and bone marrow brings hope to patients suffering from blood disorders and cancers. The distinctions are important. These patients should work with their medical teams to make informed decisions and face the process of transplantation with certainty.
For more information visit the official site:: https://www.edhacare.com/treatments/organ-transplant/bone-marrow
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